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Mariah Carey takes a tumble onstage (video) – Daily Gossip
Violation of Pakistan's sovereignty unacceptable: President
SLAMABAD, Sep 30 (APP): President Asif Ali Zardari on Thursday said the Government of Pakistan strongly disapproves any incident of violation of its sovereignty...link
Face-off between India, Pak delegates at UNGA
NEW YORK: In an unusual face-off, Indian and Pakistani diplomats engaged in heated exchanges in the UN General Assembly ( UNGA) over Jammu and Kashmir...link
Revisiting the Debate: Mammogram Benefit for Women in Their 40s?
Male and female relatives of young women with breast cancer are at greater risk of developing cancer themselves, according to research published today.
Scientists studied parents and siblings of 504 women diagnosed with the disease before the age of 35 and found they were at a 1.5 to two-fold increased risk of prostate, lung, brain and urinary cancers.
The risk was little changed among the relatives of women who did not carry known faulty genes that increase the chance of breast cancer. That suggested there may be other undiscovered gene disorders causing cancer in young women and their families, the researchers said, meaning further work could help identify more people who might be susceptible.
Women who inherit one of the abnormal genes known as BRCA1 and BRCA2 have a 55% to 85% risk of developing breast cancer in their lifetime. But most women with the disease do not have the high-risk genes, which only account for between 2% and 5% of all breast cancers.
Professor John Hopper, from the Centre for Molecular, Environmental, Genetic and Analytic Epidemiology at the University of Melbourne, who led the study published in the British Journal of Cancer (BJC), said: "These results are surprising and novel, and could be pointing to a new cancer genetic syndrome.
"Just as the link between male and female breast cancers in some families led UK researchers to find the breast cancer susceptibility gene BRCA2, the results of this study could help scientists discover new cancer susceptibility genes." Dr Lesley Walker, the director of cancer information at Cancer Research UK, which owns the BJC, said: "These early results are interesting in pointing to some increased risks of other cancers in the relatives of very young breast cancer cases. This study is important in suggesting a strategy to help identify other genes which significantly increase a woman's breast cancer risk. More studies with larger numbers will help confirm these risks."
It is already known that relatives of early onset breast cancer patients without mutations in BRCA1 and BRCA2 carry up to a four-fold increased risk of the disease compared with those with no family link, but this study suggests close relatives also face higher chances of other cancers.
It also backed up earlier research by finding that mothers and sisters of women with breast cancer had a substantially increased risk of the disease, even if the women did not have a BRCA mutation. The risk for sisters was greater than for mothers. Previous studies have suggested increased risks of other cancers for relatives of women with breast cancer, but the links have been weak and inconsistent.
Of the 504 women in the study, 41 had a BRCA mutation. A total of 2,200 parents and siblings were involved.
US envoy plans more talks with Abbas, Netanyahu
Mr Netanyahu, who goes back into peace talks with the Palestinians on Tuesday in Egypt, talked at the weekend about a compromise on the extension of a 10-month moratorium on settlement construction to both Tony Blair, the Middle East envoy, and later his cabinet. But this prompted immediate outrage from Jewish settlers, a constituency with considerable leverage over his broad coalition.
Settlers, who celebrated Mr Netanyahu's election last year, accused him of betrayal and of wilting under US pressure. The moratorium on construction in the disputed territories of the West Bank expires in the last week of this month and until now Mr Netanyahu has firmly denied that any extension would be possible. Mahmoud Abbas, the Palestinian leader, has threatened to leave the talks if settlement construction resumes and Barack Obama, US President, last week called for the freeze to be prolonged.Mr Netanyahu, who goes back into peace talks with the Palestinians on Tuesday in Egypt, talked at the weekend about a compromise on the extension of a 10-month moratorium on settlement construction to both Tony Blair, the Middle East envoy, and later his cabinet. But this prompted immediate outrage from Jewish settlers, a constituency with considerable leverage over his broad coalition.
Settlers, who celebrated Mr Netanyahu's election last year, accused him of betrayal and of wilting under US pressure. The moratorium on construction in the disputed territories of the West Bank expires in the last week of this month and until now Mr Netanyahu has firmly denied that any extension would be possible. Mahmoud Abbas, the Palestinian leader, has threatened to leave the talks if settlement construction resumes and Barack Obama, US President, last week called for the freeze to be prolonged.
Danny Dayan, the chairman of the Yesha Council which represents the West Bank's 300,000 Jewish settlers, said: "If the freeze continues in any way, we promise to make every effort to fight against the Netanyahu government. It will be the beginning of the end."
Mr Dayan's colleagues were also incensed, with Gershon Mesika, leader of the settlers in the northern West Bank, announcing that a continuation of the freeze would amount to "a declaration of war". He added: "We would do everything possible to topple the prime minister."
Mr Netanyahu said limits could be imposed on the amount of construction that would be allowed, suggesting a smaller number of new homes than the 20,000 for which the settlers already have planning permission.
"Between zero and 20,000, there is also a middle ground," Mr Netanyahu said.
Mr Netanyahu's apparent willingness to compromise suggests that the prospect of the talks collapsing just weeks after they started could be averted. There have been indications that the Palestinians could accept some building in major settlements that are likely to become part of Israel in any proposed land swap.
Ehud Barak, Mr Netanyahu's doveish defence minister, has also put together a plan to ensure that new settlement construction is blocked by bureaucratic hurdles, according to the Israeli press.
There is no question that forcing through an agreement would carry a heavy political cost for Mr Netanyahu, even while doubts remain over his sincerity towards the peace talks. In an illustration of the difficulties that lie ahead, settlers went on the rampage in a Palestinian village in the West Bank yesterday, burning cars and daubing houses with graffiti.
On the Palestinian side, the hardline Islamists of Hamas are also implacably opposed to the talks and there has been an upsurge in recent days in rockets fired from Gaza, the territory which the group controls..
Disputed land in Ayodhya Ram's birthplace, but split it: High Court
The HC gave its stamp of judicial approval to the Hindu belief that Lord Ram was indeed born there. The court also ruled by a majority verdict that the disputed 120 feet by 90 feet plot land be divided into three equal parts among three petitioners ...link
NRO beneficiaries resign voluntarily; no threat to govt: Gilani
Pakistani Prime Minister Yusuf Raza Gilani has cancelled visits starting this month to Europe, the foreign ministry said, a move which could intensify media speculation that pressure is mounting for a change in government.
The government's perceived poor handling of summer floods has raised questions over political stability in Pakistan, a nuclear-armed country fighting homegrown Taliban insurgents which the U.S. regards as vital to efforts to stabilise Afghanistan.
"In view of his pre-occupations with the post-flood situation, the Prime Minister has decided not to go ahead with his scheduled visits to Paris and Brussels," said a Ministry of Foreign Affairs spokesman in a statement.
"(The) Prime Minister's official visit to France is being re-scheduled."
Foreign Minister Shah Mehmood Qureshi will lead Pakistan's delegation to the Asia-Europe summit in Brussels next month, said the statement.
Pakistani leaders have said the government has done its best to help flood victims given its limited resources and have appealed for international aid to help with reconstruction.
The military has taken the lead in relief and rescue efforts, reinforcing the view that it's Pakistan's most decisive and efficient institution in times of crises.
Those dynamics have raised questions in the Pakistani media and elsewhere about the fate of the civilian government.
"No one knows if Gilani decided at the spur of the moment to cancel his visit, or he was advised not to travel abroad in the face of the urgency the government is facing because of the floods and the pressure for a change in government," said an article in Pakistan's The News on Saturday.
The newspaper has been outspoken against several Pakistani governments over the years.
Gilani's press secretary, Shabbir Anwar, said he had been scheduled to leave at the end of this month for Paris with a delegation of 40 other officials to meet French President Nicolas Sarkozy and then travel from there on Oct 1 to Brussels.
Instead Gilani decided to stay behind and the size of the delegation was reduced to save on expenses after the floods.
"This had nothing to do with politics," Anwar told Reuters.
The military, which has ruled Pakistan for more than half of its history, has held huge sway over security and foreign policy, even while civilian governments have been in power.
"Recent rumours of a pending military coup are fueled by politicised private media groups, which hope to undermine the Pakistan People's Party (PPP) led government of President Asif Ali Zardari," said Eurasia consultancy group.
Even though Pakistan has a history of military coups, analysts say one is unlikely now because the army would inherit the flood disaster, and a takoever could make Western donors hesitant to provide aid for reconstruction after floods.
It may, however, try to manipulate Pakistani politics from behind the scenes, Eurasia said.
PPP spokeswoman Fauzia Wahab said it had asked Gilani to meet other political parties to "counter these rumours" about a possible change in government.
"It's a war of nerves. Whenever our party is in power some factions (parties) gang up together and keep on conspiring against us," she said, adding that the military was not involved in the "campaign" because it could not afford to shift its focus away from the fight against Taliban insurgents.
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